Clinical Advisory Board
John Kellum, MD
John Kellum, M.D. is Professor and Vice Chair for Research, Director, The Center for Critical Care Nephrology (formerly the Bioengineering and Organ Support Program), CRISMA Center, Director, Center for Assistance in Research using eRecord (CARe). As a clinician scientist, his research interests span various aspects of Critical Care Medicine, but center in critical care nephrology (including acid-base, and renal replacement therapy), sepsis and multi-organ failure (including blood purification), and clinical epidemiology. His research has received continuous funding from the National Institutes of Health since 2001, and he has active funding from multiple different NIH Institutes. Dr. Kellum has authored more than 300 publications and has also edited several major textbooks including Critical Care Nephrology and Stewart’s Textbook of Acid-Base.
Dr. Kellum has won several awards for teaching; he lectures widely and has given more than 300 seminars and invited lectures related to his research. Dr. Kellum has been
involved in the development of several clinical practice guidelines. He is a founding member and past president of the Acute Dialysis Quality Initiative (www.ADQI.net) and is cochair
of the Kidney Diseases Improving Global Outcomes (KDIGO) clinical practice guideline on acute kidney injury (www.kdigo.org). Finally Dr. Kellum is a leader in electronic research especially in critical illness and is the Director of CARe (Center for Assistance in Research using the eRecord) at the University of Pittsburgh (www.eresearch.pitt.edu).
Dr. Kellum received his medical degree from the Medical College of Ohio. He completed his internship and residency at University of Rochester, Strong Memorial Hospital & Affiliate Hospitals, Rochester, NY and was a fellow in Critical Care Medicine at University of Pittsburgh Medical Center, Pittsburgh, PA.
Steven Opal, MD
Steven Opal is Professor of Medicine (Research Scholar Track) in the Infectious Disease Division at The Warren Alpert Medical School of Brown University. He is Chief, Infectious Disease Division at Memorial Hospital of Rhode Island. Dr. Opal’s interests are in the field of septic shock research, endotoxin, cytokines, molecular signaling pathways, microbial mediators, microbial genetics, and antibiotic resistance. The pathophysiology of septic shock is his primary laboratory interest, including the early events that occur in the host-pathogen interaction with systemic infection. Clinical trial design, implementation and analysis from Phase I to Phase III trials is a primary clinical research focus at the present time. He is the editor of several academic research journals and three textbooks in the field of infectious diseases, endotoxin-mediated diseases and septic shock.
Dr. Opal is a member of several professional societies including the Society of Critical Care Medicine, the International Cytokine Society, the Infectious Diseases Society of America and the International Endotoxin and Innate Immunity Society. He is current chair of the International Sepsis Forum. Opal has published more than 200 peer-reviewed research articles and has edited several academic research journals as well as three textbooks on infectious diseases, endotoxin-mediated diseases and septic shock.
Dr. Opal’s received his undergraduate degree from Cornell University and a medical degree from Albany Medical School. He completed his internship and residency in internal medicine at Fitzsimons Army Medical Center in Denver, Colorado, and was a fellow in infectious diseases at Walter Reed Army Medical Center in Washington, D.C.
B. Taylor Thompson, MD
Dr. Thompson is Professor of Medicine at Harvard Medical School and Director of Pulmonary and Critical Care Translational Research at the Massachusetts General Hospital in Boston. He is a clinical trialist and serves as Medical Director of the Clinical Coordinating Center of the National Institute of Health’s Prevention and Early Treatment of Acute Lung Injury (PETAL) clinical trials network. In addition to ARDS, Dr. Thompson’s clinical and research interests include therapeutic interventions for severe sepsis. He is an internationally recognized clinical trialist and serves on a number of Data and Safety Monitoring Boards for the NIH and the pharmaceutical industry. He has written over 200 peer reviewed articles and book chapters, has participated in the development of clinical trial and educational software, and has served on two Surviving Sepsis Treatment Guideline committees.
Dr. Thompson received his undergraduate degree in Physiology from the University of California, Davis and his MD from the University of California, Davis Medical School. He completed an internal medicine residency and chief medical residency at the New England Deaconess Hospital and his pulmonary and critical care fellowship at the Massachusetts General Hospital where he subsequently joined the Staff.
Jean-Louis Vincent, MD
Dr. Vincent is Professor of intensive care at the University of Brussels, and intensivist in the Department of Intensive Care at the Erasme University Hospital in Brussels. He is President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM) and a Past-President of the Belgian Society of Intensive Care Medicine (SIZ), the European Society of Intensive Care Medicine (ESICM), the European Shock Society (ESS), and the International Sepsis Forum (ISF). He is member of the Royal Medical Academy of Belgium.
Dr. Vincent has signed more than 850 original articles, some 400 book chapters and review articles, 930 original abstracts, and has edited 99 books. He is co-editor of the Textbook of Critical Care (Elsevier Saunders) and the “Encyclopedia of Intensive Care Medicine” (Springer).
He is the editor-in-chief of “Critical Care,” “Current Opinion in Critical Care,” and “ICU Management” and member of the editorial boards of about 30 other journals (including senior editor of Critical Care Medicine). He received several awards: the Distinguished Investigator Award of the Society of Critical Care Medicine, the College Medalist Award of the American College of Chest Physicians; he was the Recipient of the “Society Medal” (lifetime award) of the European Society of Intensive Care Medicine and has received the prestigious Belgian scientific award of the FRS-FNRS (Prix Scientifique Joseph Maisin-Sciences biomédicales cliniques).